Ulysse Trélat (13 August 1828, Paris – 28 March 1890) was a French surgeon remembered for describing the Leser-Trélat sign. He was the son of an Army physician, and received his education from his father, Philippe-Frédéric Blandin, Auguste Nélaton and Philibert Joseph Roux. He graduated Doctor of Medicine in 1854, became prosector in 1855 and agrégé in 1857. He became surgeon in 1860, chief of surgery at Paris Maternité in 1864 and professor of clinical surgery at the Hôpital Necker.